A systematic review of ethical, legal, and social implications in the bioprinting literature: considerations of intellectual property and ownership
Description: This manuscript explores ethical, legal, and social considerations acknowledged by scientists in the bioprinting literature with a particular focus on IP and ownership.
Source: Caitlin Maloney, Michael Ruiz, Shouvik Majumder, and Jennifer K. Wagner
Future Directions and Emerging Issues
Description: Week 7 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Societal and Cultural Impacts
Description: Week 6 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Legal and Regulatory Challenges Part 1: Introduction
Description: Week 5 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Legal and Regulatory Challenges Part 2: Regulatory Perspective on 3D Bioprinting
Description: Week 5 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Legal and Regulatory Challenges Part 3: Past Legal Cases Applied to Bioprinting
Description: Week 5 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Legal and Regulatory Challenges Part 4: Standards and Regulation in Bioprinting
Description: Week 5 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Key Ethical Issues
Description: Week 4 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Bioprinting Applications Part 1: Introduction
Description: Week 3 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Bioprinting Applications Part 2: 3D Printed Skin
Description: Week 3 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Bioprinting Applications Part 3: Heart Disease
Description: Week 3 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Bioprinting Applications Part 4: Cultured Meat
Description: Week 3 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Introducing Bioethics
Description: Week 2 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Defining Bioprinting
Description: Week 1 | This video is designed for use with the Bioethics & Bioprinting Short Course Syllabus created in Spring 2025 by Jennifer K. Wagner, J.D., Ph.D.
Source: Laura Cabrera
Slide Deck: Bioinks for 3D Bioprinting: Revolutionizing Tissue Engineering
Description: This slide deck was prepared for use as an educational resource for instructors.
Source: İlayda Namlı and Ibrahim Ozbolat
Slide Deck: Bioprinting: Revolutionizing Medical Manufacturing
Description: This slide deck was prepared for use as an educational resource for instructors.
Source: İlayda Namlı and Ibrahim Ozbolat
Bioprinting: Foundations, Advances, and Applications
Description: This collection of landmark articles provides a curated reading list on bioprinting, covering its evolution, key techniques, material advancements, and biomedical applications. It explores the critical role of bioinks, various bioprinting strategies, and the challenges of fabricating functional tissues that mimic native organs. As the field advances, overcoming hurdles in vascularization, tissue maturation, and cell differentiation remains essential for bioprinting’s success in regenerative medicine and beyond.
Source: İlayda Namlı and Ibrahim Ozbolat
Legal and Regulatory Considerations for 3D Bioprinting
Description: This collection explores the legal and regulatory complexities of bioprinting, including the lack of clear national and international guidelines, the difficulty of clinical translation, and the classification of bioprinted constructs.
Source: Caitlin Maloney
Biomaterials for Bioprinting
Description: This video created by İlayda Namlı and Ibrahim Ozbolat provides an introduction to biomaterials used in bioprinting.
Source: İlayda Namlı and Ibrahim Ozbolat
Cell Cultures in Bioprinting
Description: This video created by İlayda Namlı and Ibrahim Ozbolat provides an introduction to maintaining healthy cell cultures used in bioprinting.
Source: İlayda Namlı and Ibrahim Ozbolat
Introduction to Bioprinting
Description: This video created by the İlayda Namlı and Ibrahim Ozbolat provides an introduction to bioprinting methods and techniques.
Source: İlayda Namlı and Ibrahim Ozbolat
Bioethics & Bioprinting Short Course Syllabus
Description: This seven-week short course was designed and piloted at Penn State in Spring 2025. It is intended as a one-credit (45 hour) college-level remote asynchronous interdisciplinary course designed for students of different disciplines. This short course provides an introduction to 3D bioprinting technologies for regenerative medicine and critical consideration of the many ethical, legal, and social issues that correspond to the development and use of these technologies.
Source: Jennifer K. Wagner
Bioprinting-Related Bioethics Discussion Board Prompts
Description: This educational resource provides example discussion board prompts designed to facilitate interactive, peer-to-peer discussions on ethical, legal, and social implications (ELSI) of bioprinting technologies.
Source: Jennifer K. Wagner
Do You Own Your Bioprinted Body? Navigating Ownership, Ethical Challenges and Regulatory Concerns
Description: Presentation by Jeremy Harbaugh on January 15, 2025 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series
Millenium Café: Boosting Bioethics & Bioprinting
Description: In this special edition of the Millennium Café, a moderated panel discussion with researchers from different disciplines consider the scientific developments and corresponding ethical, legal, and social implications of bioprinting technologies. Could bioprinted organs be a solution to the transplant organ shortage? Who owns a bioprinted organ? Are “silent” clinical trials with personalized bioprinted tissues and organs ethical? Panelists: Jennifer K. Wagner, Laura Y. Cabrera, and Ibrahim T. Ozbolat with moderator Alyna Khan.
Source: Penn State Materials Research Institute's Millenium Café - December 10, 2024
Presentation Slide Deck: Advancing Skin-on-a-Chip Models: Integrating Human-Relevant Cellular and Biomechanical Complexity
Description: The accompanying slide deck was prepared by Dr. H. Erbil Abaci for presentation on December 9, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: Dr. H. Erbil Abaci
Advancing Skin-on-a-Chip Models: Integrating Human-Relevant Cellular and Biomechanical Complexity
Description: Presentation by Dr. H. Erbil Abaci on December 9, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series
Presentation Slide Deck: 3D Bioprinting for Pediatric Congenital Heart Defect Repair: Current Technologies and Ethical Challenges
Description: The accompanying slide deck was prepared by Dr. Guohao Dai for presentation on December 6, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: Dr. Guohao Dai
3D Bioprinting for Pediatric Congenital Heart Defect Repair: Current Technologies and Ethical Challenges
Description: Presentation by Dr. Guohao Dai on December 6, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series
Presentation Slide Deck: The Role of Standards in Facilitating Bioprinting Technology: Inroads Made, More Work to be Done
Description: The accompanying slide deck was prepared by Katrina Wells for presentation on December 5, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: Katrina Wells
The Role of Standards in Facilitating Bioprinting Technology: Inroads Made, More Work to be Done
Description: Presentation by Katrina Wells on December 5, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series
Presentation Slide Deck: Regulatory Perspective on 3D Bioprinting of Regenerative Medicine and Tissue Engineered Products
Description: The accompanying slide deck was prepared by Dr. Laura Ricles for presentation on December 4, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: Dr. Laura Ricles
Regulatory Perspective on 3D Bioprinting of Regenerative Medicine and Tissue Engineered Products
Description: Presentation by Dr. Laura Ricles on December 4, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series
Presentation Slide Deck: From Biophysics to Cellular Farming: Towards Culturing Meat for Food Production
Description: The accompanying slide deck was prepared by Dr. Amy Rowat for presentation on December 3, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: Amy Rowat
From Biophysics to Cellular Farming: Towards Culturing Meat for Food Production
Description: Presentation by Amy Rowat on December 3, 2024 as part of the 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series.
Source: 2024-2025 “Boosting Bioethics & Bioprinting” Webinar Series
A narrative review: 3D bioprinting of cultured muscle meat and seafood products and its potential for the food industry.
Description: This review article explores the adoption of 3D bioprinting modalities to manufacture lab-grown muscle food products and their associated technologies, cells, and bioink formulations. Additionally, various processing techniques, governing the characteristics of bioprinted food products, nutritional compositions, and safety aspects as well as its relevant ethical and social considerations, were discussed.
Source: Gurel M, Rathod N, Cabrera LY, Voyton S, Yeo M, Ozogul F, Ozbolat IT. A narrative review: 3D bioprinting of cultured muscle meat and seafood products and its potential for the food industry. Trends Food Sci Technol. 2024 Oct;152:104670. doi: 10.1016/j.tifs.2024.104670. Epub 2024 Aug 14. PMID: 39309029; PMCID: PMC11412102.
3D Bioprinting in Tissue and Organ Regeneration
Description: 3D Bioprinting in Tissue and Organ Regeneration explores the latest advancements and biomedical applications of bioprinting. Beginning with an introduction to key techniques, bioinks, and construct design, the book provides an in-depth review of bioprinting applications in skin, cartilage, bone, and vascularized tissue. A dedicated chapter examines intraoperative bioprinting, a promising future trend, while ethical and regulatory concerns surrounding the field are also addressed. Written by three global experts, this book is designed for students and professionals with foundational knowledge of bioprinting who seek a deeper understanding of its biomedical potential. Readers will gain insights into bioprinting modalities, procedural steps, and real-world engineering and clinical perspectives, with a focus on translating bioprinting technologies from research to patient care.
Source: Yang Wu, Jerry Fuh, and Ibrahim Ozbolat. Elsevier Academic Press (2023).
Ethical challenges with 3D bioprinted tissues and organs.
Description: 3D Bioprinting is fast advancing to offer capabilities to process living cells into geometrically and functionally complex tissue and organ substitutes. As bioprinted constructs are making their way into clinic, the bioprinting community needs to consider the responsible innovation and translation of the bioprinted tissues and organs.
Source: Datta P, Cabrera LY, Ozbolat IT. Ethical challenges with 3D bioprinted tissues and organs. Trends Biotechnol. 2023 Jan;41(1):6-9. doi: 10.1016/j.tibtech.2022.08.012. Epub 2022 Sep 15. PMID: 36117024.
3D Bioprinting: Fundamentals, Principles and Applications
Description: This comprehensive guide explores the entire bioprinting process, from bioink processing to advanced organ printing and future trends. It provides an in-depth analysis of various bioprinting techniques, detailing their process modeling, physics, bioink compatibility, and key achievements. Readers will gain a step-by-step understanding of organ printing, including stem cell isolation, 3D bioprinting, and post-transplantation considerations. Additionally, the book offers strategic insights for selecting the most suitable bioprinting process for applications in tissue engineering, regenerative medicine, transplantation, clinical settings, and pharmaceuticals.
Source: Ibrahim Ozbolat. Elsevier Academic Press (2017).